Studie: Brain areas responsible for motor control in autism spectrum disorder (ASD)

The specific brain areas responsible for motor control in autism spectrum disorders (ASD) include:
  1. Primary motor cortex (Brodmann Area 4): This region is involved in the planning and execution of accurate skeletomotor movements.
  2. Lateral premotor cortex (Brodmann Area 6): This region is directly connected with the intraparietal sulcus and inferior parietal lobule (BA 5 and 7), and is involved in the planning and execution of accurate skeletomotor movements.
     
  3. Midline supplementary motor area (SMA; BA 6): This region is involved in the planning and execution of accurate skeletomotor movements.
     
  4. Intraparietal sulcus and inferior parietal lobule (BA 5 and 7): These regions are involved in the planning and execution of accurate skeletomotor movements.
     
  5. Frontal eye fields (FEF): Located in premotor cortex (BA 6), these regions are involved in initiating rapid ballistic shifts in eye gaze (i.e., saccades) and slower velocity tracking movements (i.e., smooth pursuit eye movements).
     
  6. Supplementary eye fields (SEF): Located on the medial surface of the superior frontal gyrus (BA 6 and 8), these regions are involved in the preparatory phase of eye movements, sequencing multiple saccades, and coordinating eye and body movements.
     
  7. Middle frontal gyrus (BA 9 and 46): Located in dorsolateral prefrontal cortex (DLPFC), these regions are involved in cognitive control of eye movements, including inhibiting context-inappropriate eye movements, error monitoring, short-term spatial memory, and decision processes.
     
  8. Parietal eye fields (PEF): Located in the intraparietal sulcus and parietal-occipital junction (BA 7 and 39), these regions are involved in generating conjugate eye movements and shifting visual attention.
     
  9. Cerebellum: This region is involved in generating reflexive eye movements and calibrating eye movement accuracy.
     
These brain areas are responsible for motor control in ASD, and their dysfunction can lead to various motor impairments, such as reduced postural stability, upper extremity dysfunction, compromised movement preparation and planning, and oculomotor dysfunction
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